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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRK
All Species:
18.48
Human Site:
Y46
Identified Species:
33.89
UniProt:
P42685
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42685
NP_002022.1
505
58254
Y46
Q
S
Q
R
H
G
H
Y
F
V
A
L
F
D
Y
Chimpanzee
Pan troglodytes
XP_518702
505
58217
Y46
Q
S
Q
R
H
G
H
Y
F
V
A
L
F
D
Y
Rhesus Macaque
Macaca mulatta
XP_001112190
505
58228
Y46
Q
S
Q
R
H
G
R
Y
F
V
A
L
F
D
Y
Dog
Lupus familis
XP_539091
505
57709
Y53
P
Q
P
G
G
G
R
Y
F
V
A
L
F
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q922K9
512
58825
Y53
P
E
R
S
H
G
Q
Y
F
V
A
L
F
D
Y
Rat
Rattus norvegicus
Q62662
506
58147
Y47
A
N
R
S
Q
G
Q
Y
F
V
A
L
F
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02977
536
59984
P68
F
S
G
P
G
F
Y
P
C
N
T
L
Q
A
H
Frog
Xenopus laevis
P13406
537
60828
S69
T
V
F
G
G
V
N
S
S
S
H
T
G
T
L
Zebra Danio
Brachydanio rerio
XP_695937
480
54879
L47
S
F
N
A
G
D
K
L
E
P
I
T
K
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
P51
Q
P
P
E
Q
I
R
P
V
P
Q
I
P
E
S
Honey Bee
Apis mellifera
XP_396043
451
51726
P22
K
P
D
R
I
G
N
P
N
I
E
A
V
A
S
Nematode Worm
Caenorhab. elegans
NP_493502
507
57512
N48
I
A
A
S
S
S
G
N
T
I
D
K
N
Q
N
Sea Urchin
Strong. purpuratus
NP_001135852
530
59779
A50
G
S
H
I
V
V
N
A
P
P
P
H
P
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.6
80.5
N.A.
88.6
88.3
N.A.
N.A.
48.5
48.4
60.5
N.A.
56.8
51.6
50.4
56.6
Protein Similarity:
100
99.8
98
87.7
N.A.
92.9
93
N.A.
N.A.
64.7
64.2
74
N.A.
73.3
67.1
69.4
70.5
P-Site Identity:
100
100
93.3
60
N.A.
66.6
60
N.A.
N.A.
13.3
0
0
N.A.
6.6
13.3
0
6.6
P-Site Similarity:
100
100
93.3
60
N.A.
73.3
73.3
N.A.
N.A.
26.6
6.6
0
N.A.
20
33.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
0
0
8
0
0
47
8
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
8
0
0
47
0
% D
% Glu:
0
8
0
8
0
0
0
0
8
0
8
0
0
8
8
% E
% Phe:
8
8
8
0
0
8
0
0
47
0
0
0
47
0
0
% F
% Gly:
8
0
8
16
31
54
8
0
0
0
0
0
8
8
0
% G
% His:
0
0
8
0
31
0
16
0
0
0
8
8
0
0
8
% H
% Ile:
8
0
0
8
8
8
0
0
0
16
8
8
0
0
0
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
54
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
24
8
8
8
0
0
8
0
8
% N
% Pro:
16
16
16
8
0
0
0
24
8
24
8
0
16
0
0
% P
% Gln:
31
8
24
0
16
0
16
0
0
0
8
0
8
8
0
% Q
% Arg:
0
0
16
31
0
0
24
0
0
0
0
0
0
0
0
% R
% Ser:
8
39
0
24
8
8
0
8
8
8
0
0
0
8
16
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
8
16
0
8
0
% T
% Val:
0
8
0
0
8
16
0
0
8
47
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
47
0
0
0
0
0
0
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _